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MR Angiography of Peripheral Arterial Disease Click on any image below to see an enlargement of that image. Above images are all original MR scans performed at Parkside MR Center. Discussion Peripheral arterial disease (PAD) is usually a manifestation of systemic atherosclerosis. As such it has the same major risk factors (diabetes mellitus, smoking, high cholesterol, and hypertension) and co-existent coronary artery disease is common. The main symptoms of PAD are intermittent claudication and ischemic rest pain. Patients with advanced disease often have diminished/absent pulses and non-healing ulcers. The initial evaluation of patients with signs and symptoms of PAD usually involves taking systolic blood pressures from the arm and ankle and calculating the ankle-brachial index. Supplemental studies include segmental limb pressures, pulse volume recordings, toe pressures, and Duplex US interrogation. These studies can be performed at rest and after exercise-induced ischemia. Once it has been determined that surgery is an option for a patient with severe PAD, the vascular surgeon will want a pre-operative anatomic roadmap of the arteries. This requires evaluation of the pelvic inflow arteries and the run-off arteries down to the mid-foot level. Also patients with recurrent symptoms after surgery require evaluation of their by-pass grafts. MRA is uniquely suited to meet these requirements without exposing the patient to ionizing radiation, arterial puncture, or nephrotoxic-iodinated contrast. In fact, MRA has almost completely replaced conventional angiography for this purpose. Until recently, MRA of the legs was performed without contrast using time-offlight MRA. While this technique is good, it is also time consuming, taking 60-90 minutes to image from the renal arteries to the mid-feet. Although most of the technology for fast contrast-enhanced MRA was available in the late 1990s, and successfully applied to the arteries above the legs, the length of coverage needed for the legs was still an obstacle for peripheral MRA. Finally a few years ago, the advent of parallel imaging and whole-body surface coil technology has enabled fast, high-resolution, contrast-enhanced, peripheral MRA. Now the arteries from the renals to the mid-feet can be imaged in less than 1 minute. Copyright © 2008
Parkside Magnetic Resonance Center |